Fig. 12From: Lasmiditan and 5-Hydroxytryptamine in the rat trigeminal system; expression, release and interactions with 5-HT1 receptorsCorrelation of in situ 5-HT and CGRP release from the same dural or trigeminal ganglion samples. AÂ Correlations of constitutive release (all baseline measurements) from the dura, soma-poor and soma rich TG. A significant negative correlation was observed. BÂ Correlations of constitutive release from the soma-rich TG only, and here a significant negative correlation was observed. CÂ The stimulated release (addition of 60 mM KCl (K+) or (D) 100 nM capsaicin, of 5-HT and CGRP from the same soma-rich TGs. Significant positive correlation was observed for K+ which contrasts to negative correlation observed with capsaicin. Data are shown as individual data points with p values and R2 obtained from the correlation analysisBack to article page