Table 2 Amplitude and duration of CSD in different nVNS paradigms
| Â | n | CSD amplitude (mV) | CSD duration (s) |
|---|---|---|---|
Amplitude-response | Â | Â | Â |
Sham stimulation | 6 | 21\(\pm\)1.5 | 19\(\pm\)1.7 |
Low intensity nVNS | 6 | 25\(\pm\)0.8 | 15\(\pm\)0.6 |
Medium intensity nVNS | 6 | 21\(\pm\)2.5 | 18\(\pm\)1.9 |
High intensity nVNS | 6 | 19\(\pm\)2.4 | 21\(\pm\)2.7 |
Dose-response | Â | Â | Â |
Sham stimulation | 8 | 20\(\pm\)0.6 | 23\(\pm\)3.8 |
2\(\times\)2-min nVNS | 8 | 20\(\pm\)1.3 | 21\(\pm\)0.7 |
3\(\times\)2-min nVNS | 9 | 21\(\pm\)1.1 | 21\(\pm\)1.3 |
1\(\times\)6-min nVNS | 8 | 20\(\pm\)0.8 | 21\(\pm\)1.0 |
Chronic treatment | Â | Â | Â |
Daily nFNS | 6 | 20\(\pm\)0.4 | 20\(\pm\)0.4 |
Daily nVNS | 8 | 20\(\pm\)0.7 | 21\(\pm\)0.5 |