Fig. 2

A Eight acute noxious thermal stimuli were delivered to the corner of the mouth in controls, migraineurs during the interictal phase and in migraineurs in the 24 h immediately prior to a migraine headache; (B) Mean ± SEM pain intensity ratings over the 8 noxious stimuli for each group; (C) Mean ± SEM pain intensity ratings for each of the 8 noxious stimuli in each group; (D) Mean ± SEM administered thermode temperatures for each of the three groups. Note there were no significant differences in pain intensity rating or thermode temperatures between any of the groups