Skip to main content
Fig. 3 | The Journal of Headache and Pain

Fig. 3

From: Insulin sensitizes neural and vascular TRPV1 receptors in the trigeminovascular system

Fig. 3

Changes in meningeal blood flow induced by topical application of capsaicin at low concentration. (A) Flowchart summarizing the experimental protocol. (B) Blood flow increasing effect of capsaicin (10 nM for 3 min) before and after insulin (10 μM for 10 min) applied topically to the dura mater. The light grey bar indicates the effect of insulin application alone, coloured bars indicate the capsaicin-induced changes in blood flow. The number of measurements is indicated in the bars. *: statistically different from the basal flow. #: statistically different from the effect without pretreatment

Back to article page