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Fig. 6 | The Journal of Headache and Pain

Fig. 6

From: IL-17 crosses the blood–brain barrier to trigger neuroinflammation: a novel mechanism in nitroglycerin-induced chronic migraine

Fig. 6

NTG promoted microglial inflammatory polarization in the TNC. (A) Images of Iba1 and CD68 costaining in the TNC of rats with NTG-induced migraine. (D) The ratio of Iba+/CD68+ cells. (B) Images of Iba1 and NF-κB p-p65 costaining in the TNC of rats with NTG-induced migraine. (E) The ratio of Iba+/ NF-κB p65+ cells. (C) Images of Iba1 and iNOS costaining in the TNC of rats with NTG-induced migraine. (F) The ratio of Iba+/ iNOS+ cells. Statistical analysis was performed using one–way ANOVA, n = 3, *p < 0.05 compared to the control group

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