Fig. 5
Disrupting NMDA receptor-Fyn but not -Src interaction reduced cortical susceptibility to CSD in mouse brain slices. a b Representative traces of 1st peak of CSD affected by Kreb’s, 1 μM TAT-Fyn (39-57), 1 μM TAT-Fyn (39-57) SC, 1 μM TAT-Fyn (39-57) + 300 μM BzATP, 1 μM TAT-Src (40-49) and 1 μM TAT-Src (40-49) SC. c d Effects of Kreb’s, 1 μM TAT-Fyn (39-57), 1 μM TAT-Fyn (39-57) SC, 1 μM TAT-Fyn (39-57) + 300 μM BzATP, 1 μM TAT-Src (40-49) and 1 μM TAT-Src (40-49) SC on CSD latency and propagation rate. Two-tailed unpaired t-test was used for comparison in CSD latency and propagation rate between Kreb’s and TAT-Fyn (39-57) group, TAT-Fyn (39-57) and TAT-Fyn (39-57) SC group, TAT-Fyn (39-57) and TAT-Fyn (39-57) + BzATP group, Kreb’s and TAT-Src (40-49) group, TAT-Src (40-49) and TAT-Src (40-49) SC group. Significant differences were indicated by * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001