Fig. 2

Change in weekly migraine days in A) participants aged ≥60 years and B) overall population. LSM, least-squares mean; LSMD, least-squares mean differences; SE, standard error. Data shown are the LSM changes from baseline in the weekly average number of migraine days over the first 4 weeks of double-blind treatment. ^aP < 0.01 vs placebo. ^bP < 0.05 vs placebo. ^cP < 0.0001 vs placebo