Table 4 Incidence rates and hazard ratios for ischemic stroke, coronary heart disease and cardiovascular disease events associated with a history of migraine among patients with a history of cardiovascular disease

 Number of events

2195

765

 Follow-up in person-years

227,257

58,097

 Incidence rate (95% CI)^a

9.7 (9.3, 10.1)

13.2 (12.2, 14.1)

  Model 1

1 (ref)

1.37 (1.26, 1.48)

  Model 2

1 (ref)

1.39 (1.28, 1.51)

  Model 3

1 (ref)

1.25 (1.15, 1.36)

  Model 4

1 (ref)

1.27 (1.17, 1.39)

 Number of events

6304

1677

 Follow-up in person-years

217,059

55,859

 Incidence rate (95% CI)^a

29.0 (28.3, 29.8)

30.0 (28.6, 31.5)

  Model 1

1 (ref)

1.04 (0.99, 1.10)

  Model 2

1 (ref)

1.04 (0.98, 1.09)

  Model 3

1 (ref)

0.99 (0.93, 1.04)

  Model 4

1 (ref)

0.99 (0.93, 1.05)

 Number of events

8062

2301

 Follow-up in person-years

213,557

54,347

 Incidence rate (95% CI)^a

37.8 (36.9, 38.6)

42.3 (40.6, 44.1)

  Model 1

1 (ref)

1.13 (1.08, 1.18)

  Model 2

1 (ref)

1.13 (1.08, 1.18)

  Model 3

1 (ref)

1.06 (1.01, 1.11)

  Model 4

1 (ref)

1.06 (1.01, 1.12)