Table 1 Characteristics of patients without a history of cardiovascular disease who had and did not have a history of migraine
| Â | History of Migraine | |
|---|---|---|
No (n = 87,960) | Yes (n = 21,990) | |
Calendar year of the index date, N (%) | ||
 2008 | 9268 (10.5) | 2317 (10.5) |
 2009 | 5648 (6.4) | 1412 (6.4) |
 2010 | 5368 (6.1) | 1342 (6.1) |
 2011 | 6076 (6.9) | 1519 (6.9) |
 2012 | 6596 (7.5) | 1649 (7.5) |
 2013 | 8200 (9.3) | 2050 (9.3) |
 2014 | 10,744 (12.2) | 2686 (12.2) |
 2015 | 10,348 (11.8) | 2587 (11.8) |
 2016 | 12,164 (13.8) | 3041 (13.8) |
 2017 | 13,548 (15.4) | 3387 (15.4) |
Age, years, N (%) | ||
 66–70 | 55,096 (62.6) | 13,774 (62.6) |
 71–75 | 16,948 (19.3) | 4237 (19.3) |
 76–80 | 8660 (9.8) | 2165 (9.8) |
 81–85 | 4504 (5.1) | 1126 (5.1) |
 ≥ 86 | 2752 (3.1) | 688 (3.1) |
Age, years, mean (SD) | 71.3 (5.6) | 70.8 (5.8) |
Females, N (%) | 74,616 (84.8) | 18,654 (84.8) |
Race/Ethnicity, N (%) | ||
 Non-Hispanic Black | 6353 (7.2) | 818 (3.7) |
 Non-Hispanic White | 75,573 (85.9) | 20,030 (91.1) |
 Hispanic | 1435 (1.6) | 317 (1.4) |
 Asian | 1750 (2.0) | 211 (1.0) |
 Other | 2849 (3.2) | 614 (2.8) |
Low-income subsidy, N (%) | 19,343 (22.0) | 4135 (18.8) |
Area level median income, N (%) | ||
 < $35,000 | 6204 (7.1) | 1193 (5.4) |
 $35,000 - $49,999 | 26,285 (29.9) | 5935 (27.0) |
 $50,000 - $74,999 | 33,563 (38.2) | 8476 (38.5) |
 ≥ $75,000 | 21,908 (24.9) | 6386 (29.0) |
Smoking, N (%) | 6783 (7.7) | 2669 (12.1) |
Diabetes, N (%) | 19,873 (22.6) | 3780 (17.2) |
Hypertension, N (%) | 55,190 (62.7) | 13,264 (60.3) |
Chronic kidney disease, N (%) | 11,009 (12.5) | 3132 (14.2) |
History of heart failure, N (%) | 3240 (3.7) | 825 (3.8) |
Depression, N (%) | 8783 (10.0) | 4730 (21.5) |
Anxiety disorders, N (%) | 8008 (9.1) | 4222 (19.2) |
Insomnia, N (%) | 3865 (4.4) | 2141 (9.7) |
History of dementia, N (%) | 3776 (4.3) | 999 (4.5) |
Cancer, N (%) | 13,191 (15.0) | 4231 (19.2) |
Epilepsy, N (%) | 1669 (1.9) | 993 (4.5) |
Hospitalization in the prior year, N (%) | 8714 (9.9) | 5323 (24.2) |
Medication use, N (%) | ||
 Antihypertensive medication | 48,837 (55.5) | 11,887 (54.1) |
 Glucose-lowering medication | 11,987 (13.6) | 2063 (9.4) |
 Statins | 29,473 (33.5) | 7247 (33.0) |
 Non-statin lipid-lowering medication | 2901 (3.3) | 793 (3.6) |
 Medication for insomnia | 11,604 (13.2) | 7039 (32.0) |
 Hormone replacement therapy among women | 4473 (6.0) | 2260 (12.1) |
Migraine with aura, N (%) | – | 2657 (12.1) |