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Fig. 1 | The Journal of Headache and Pain

Fig. 1

From: Enhanced functional connectivity between habenula and salience network in medication-overuse headache complicating chronic migraine positions it within the addiction disorders: an ICA-based resting-state fMRI study

Fig. 1

Summary of the current study. This figure is a concise summary of the current study. MOH + CM (medication-overuse headache + chronic migraine) was shown as MOHCM here for a better layout in this figure. The picture of brain on the right shows the habenula and its connections with other brain regions. The full lines with arrows connect regions which the habenula has afferent inputs from or efferent outputs to on structural basis. The dotted lines represent functional connectivity identified by fMRI studies. Hb, habenula; SNc, substantia nigra pars; IPN, interpeduncular nucleus; DRN, dorsal raphe nucleus; MRN, median raphe nucleus; VTA, ventral tegmental area; PAG, periaqueductal gray; RMTg, rostromedial tegmental nucleus; EP, entopeduncular nucleus; NAc, nucleus accumbens; CP, caudate/putamen; LH, lateral hypothalamic; dACC, dorsal anterior cingulate cortex; mPFC, medial prefrontal cortex

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The Journal of Headache and Pain

ISSN: 1129-2377

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