Fig. 1

Comparison of precentral cortex thickness and volume between S1 and S2 scans. Legend: S1: MRI scan performed during spontaneous migraine attack; S2: MRI scan performed during inter-ictal period; PAIN side refers to the side of spontaneous migraine attack recorded at T1. Panel A: thickness of precentral cortex was significantly lower during S1 (factor SESSION: p = 0.023), without significant association with the pain side (factor SIDE: p = 0.434, interaction SESSIONxSIDE: p = 0.515). Panel B: volume of precentral cortex was significantly lower during S1 (factor SESSION: p = 0.018), without significant association with the pain side (factor SIDE: p = 0.497, interaction SESSIONxSIDE: p = 0.276)