Fig. 6From: Repeated oxytocin prevents central sensitization by regulating synaptic plasticity via oxytocin receptor in a chronic migraine mouse modelEffect of OT on synapse-associated protein expression levels. A Representative WB bands showing the expression of PSD-95, syt-1, and snap25. B, C, and D Quantification of PSD-95 (B), syt-1 (C), and snap25 (D) protein levels showed that these proteins were significantly increased in the NTG + vehicle group compared to the sham group. The expression levels of these three proteins after OT treatment were reduced, while L368,899 blocked these effects. One-way ANOVA with Dunnett’s post hoc test, n = 6/group; ***p < 0.001 vs. the sham group; ###p < 0.001 vs. the NTG + vehicle group; &&p < 0.01, &&&p < 0.001 vs. the NTG + OT groupBack to article page