Table 4 Functional enrichment results of PBMC RNA-seq data of the ictal vs. healthy comparison. DE list enrichment: overrepresentation of functional terms in the differentially expressed gene list. Ranked list enrichment: enrichment of genes associated with a certain pathway towards the top of the ranked whole data. GO: gene ontology, BP: biological process, CC: cellular component, MF molecular function. KEGG: Kyoto Encyclopedia of Genes and Genomes. Annotated: number of genes associated with the given term. R: Reactome database. Significant: number of statistically significant associated with the given term. Expected: expected number of genes associated with the given term in the DE gene list. Gene ratio: ratio of number of genes in the DE list that overlap with genes associated with the given term, and the number of genes in the DE list which overlap with genes associated with all terms in the Reactome database. Bg ratio: ratio of the number of genes associated with the given term, and the total number of genes associated with Reactome terms

From: Identification of disease- and headache-specific mediators and pathways in migraine using blood transcriptomic and metabolomic analysis