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Fig. 1 | The Journal of Headache and Pain

Fig. 1

From: Phenome-wide analysis highlights putative causal relationships between self-reported migraine and other complex traits

Fig. 1

Potentially causal associations for migraine. Causal architecture plots illustrating the latent causal variable exposome-wide analysis results. Each dot represents a trait with a significant genetic correlation with migraine. The y-axis shows the genetic causality proportion (GCP) absolute Z-score (statistical significance), whilst the x-axis exhibits the GCP estimate. The red dashed lines represent the statistical significance threshold (FDR < 5 %), while the division for traits causally influencing migraine (on the left ) and traits causally influenced by migraine (on the right) is represented by the grey dashed lines. Phenotypes in blue show a positive genetic correlation with migraine, while phenotypes in red show a negative genetic correlation with migraine

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The Journal of Headache and Pain

ISSN: 1129-2377

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