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Table 1 Headache characteristics and potential trigger factors during the 28-day period before and the first 28 days of the lockdown period in Germany

From: Primary headaches during the COVID-19 lockdown in Germany: analysis of data from 2325 patients using an electronic headache diary

 

Before lockdown

First lockdown month

p value

95%-CI

d

Monthly headache days (MHD)

7.01 ± 5.64

6.89 ± 5.47

> 0.999

−0.03 – 0.27

0.022

Monthly migraine days (MMD)

4.98 ± 4.97

4.95 ± 4.83

> 0.999

−0.11 – 0.16

0.006

Monthly days with acute medication use (AMD)

4.50 ± 3.88

4.27 ± 3.81

< 0.001*

0.19–0.35

0.060

Migraine pain intensity (NRS 0–10)

5.30 ± 1.77

5.35 ± 1.75

> 0.999

−0.10 – 0.01

0.028

Headache intensity (NRS 0–10)

4.90 ± 1.71

4.92 ± 1.72

> 0.999

−0.09 – 0.01

0.011

Activity Level (NRS 0–10)

4.82 ± 1.56

4.76 ± 1.62

0.001*

0.03–0.09

0.038

Energy Level (NRS 0–10)

5.28 ± 1.42

5.34 ± 1.47

< 0.001*

−0.08 – − 0.04

0.041

Mood (NRS 0–4)

2.42 ± 0.53

2.45 ± 0.56

< 0.001*

−0.04 – − 0.02

0.055

Stress level (NRS 0–10)

3.81 ± 1.83

3.38 ± 1.86

< 0.001*

0.40–0.46

0.233

Sleep duration (h)

7.68 ± 0.79

7.87 ± 0.82

< 0.001*

−0.20 – − 0.17

0.236

Sleep quality (NRS 0–10)

5.96 ± 1.57

5.97 ± 1.61

> 0.999

−0.03 – 0.01

0.006

  1. Values are mean ± standard deviation. NRS numeric rating scale, CI confidence interval. * = statistically significant. d = effect size, expressed as Cohen’s d.