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Table 3 Comparison of cytokines and interleukins by MWU test

From: Cytokine and interleukin profile in patients with headache and COVID-19: A pilot, CASE-control, study on 104 patients

Variable

Entire study sample

Headache patients

Non-headache patients

P value

BDNF

56.5 (35. 1-160.9)

54.3 (35. 4-154)

60.5 (33. 9-184.5)

0.928

EGF

2.1 (0. 7-8.3)

2.7 (1. 2-11.2)

1.7 (0. 5-7.3)

0.191

Eotaxin

13.8 (9. 6-19.2)

12.8 (9. 1-20.6)

13.9 (10. 3-19.1)

0.460

FGF2

0.9 (0. 3-2.7)

1.5 (0. 6-3.0)

0.6 (0. 2-2.2)

0.064

GMCSF

11.3 (5. 4-29.7)

13.3 (7. 9-40.7)

10.5 (4. 3-28.1)

0.085

GROa

3.0 (1. 3-5.6)

3.8 (2. 4-7.1)

2.7 (1. 2-4.5)

0.046

HGF

162 (104. 4-322)

167 (87. 2-281.5)

161 (104. 9-384-5)

0.625

IFNa

0.5 (0. 1-1.8)

0.5 (0. 2-1.2)

0.5 (0. 1-2.1)

0.997

IFNg

8.8 (5. 6-12.3)

10.4 (7. 5-15.1)

7.9 (5. 2-11.7)

0.073

IL1a

2.3 (0. 4-8.5)

3.0 (0. 7-13.9)

2.2 (0. 4-8.1)

0.402

IL1b

6.3 (2. 7-13.1)

7.6 (4. 1-15.0)

5.5 (2. 6-13.8)

0.120

IL10

1.7 (1. 1-3.8)

2.5 (1. 6-4.3)

1.4 (1.0–3.3)

0.008

IL12p70

3.5 (2. 3-5.3)

4.3 (3.0–5.6)

3.1 (2. 1-5)

0.061

IL13

1.9 (0. 9-3.7)

2.7 (1. 5-4.7)

1.7 (0. 8-3.3)

0.101

IL15

13.2 (6. 6-24.5)

16 (10.0–24.3)

12.6 (5. 8-26.4)

0.295

IL17a

7.0 (3. 1-18.7)

11.8 (4. 5-19.6)

5.3 (2. 7-17.6)

0.139

IL18

46.4 (24. 2-77.8)

25.6 (29. 6-84.5)

49 (23. 5-75.9)

0.968

IL1RA

579 (230. 6-1293.7)

986.5 (409. 6-1895)

466 (165–981)

0.03

IL2

13.0 (6. 9-26.6)

13.3 (7. 5-30.7)

12.6 (6. 6-26.2)

0.550

IL21

3.3 (0. 6-11.5)

7.5 (2. 6-16.7)

1.8 (0. 5-8.8)

0.022

IL22

3.6 (0. 3-22.8)

12.9 (1. 8-57.6)

2.1 (0. 2-15.2)

0.027

IL23

7.6 (3. 8-12.4)

10.0 (6. 3-13.5)

6.8 (3. 4-11.5)

0.065

IL27

15.8 (4. 9-38.8)

28.1 (10. 7-90.1)

12.7 (4. 5-32.6)

0.067

IL31

5.2 (2. 3-9.7)

7.2 (4. 3-10.7)

3.9 (2. 1-9.3)

0.068

IL4

5.4 (2. 8-9.7)

7.8 (4. 1-10.0)

5.0 (2. 6-9.0)

0.135

IL5

4.9 (1. 3-18.5)

7.6 (3.0–25.2)

5.0 (2. 6-8.9)

0.105

IL6

12.6 (5. 6-29.7)

19.6 (7. 2-35.1)

10.0 (4. 6-24.3)

0.099

IL7

1.6 (0. 6-3.6)

1.7 (0. 8-3.4)

1.4 (0. 6-4.1)

0.934

IL8

1.9 (0. 6-4.3)

1.8 (1. 1-2.8)

2.0 (0. 5-5.4)

0.991

IL9

2.1 (1.0–4.2)

2.9 (1. 7-4.9)

1.7 (0. 9-3.9)

0.064

IP1b

48.6 (32. 5-77.6)

51.2 (33. 6-90.4)

48 (29. 7-71.1)

0.295

IP10

46.2 (29. 7-71.5)

49.8 (35. 4-68.9)

45.3 (27. 4-71.7)

0.547

LIF

14.9 (7. 8-25.1)

17.5 (10. 1-25.6)

14.6 (6. 8-25.3)

0.449

MCP1

38.1 (24. 1-56.2)

34.3 (25. 3-48.8)

42.0 (23. 8-57.1)

0.396

MIP1a

3.2 (1. 4-13.1)

3.9 (2. 2-11.0)

3.1 (1. 3-13.9)

0.423

NGFb

4.1 (2. 7-5.9)

4.6 (3. 5-6.0)

3.7 (2. 5-5.7)

0.193

PDGFBB

303.4 (89. 7-771)

286 (77. 6-777.3)

331.3 (106–782)

0.888

PIGF1

5.0 (0. 7-65.0)

4.4 (0. 9-72.3)

5.4 (0. 6-60.1)

0.825

RANTES

22.5 (16. 8-36.3)

19.6 (15. 4-31.3)

24.2 (17. 8-36.7)

0.110

SCF

6.5 (3. 4-10.9)

6.9 (2. 3-10.1)

6.2 (3. 5-11.9)

0.599

SDF1a

677.7 (485–1094.8)

786 (476–1735)

628.5 (48 4-1019)

0.335

TNFa

5.9 (3. 4-14.3)

8.0 (4.4–14.8)

5.7 (3. 2-12.9)

0.333

TNFb

3.2 (1. 7-5.9)

4.2 (2. 6-6.5)

2.6 (1. 5-5.4)

0.055

VEGFA

124.1 (69.0–286.4)

124.5 (85. 4-333)

123.8 (64. 6-251)

0.555

VEGFD

12.6 (7. 2-20.6)

12.6 (5. 4-19.7)

12.6 (7. 4-20.6)

0.432