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Table 3 Interaction results found between NRXN2*SYT1; NRXN2*CASK and NRXN2*GABRE, assessed by a logistic regression analysis

From: A genetic interaction of NRXN2 with GABRE, SYT1 and CASK in migraine patients: a case-control study

Interaction OR Migraine CI 95% P-value
NRXN2*SYT1
 rs477138*rs1732664    0.10
 CC*TT 1.00
 GC*CT 0.34 0.14–0.82 0.02
NRXN2*CASK
 rs477138*rs2244325*rs2998250    0.30
 CC*AA*AA 1.00
 GG*GG*CC 0.08 0.01–0.75 0.03
NRXN2*GABRE
 rs477138*rs1158605    0.001
 CC*GG 1.00
 CG*GT 4.78 1.76–12.97 0.002
  1. NRXN2 Neurexin II, SYT1 Synaptotagmin 1, GABRE Gamma-aminobutyric acid type A receptor epsilon subunit, OR Odds ratio, CI Confidence interval. (α = 0.02, after Bonferroni correction)