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Table 8 Preventive medication against episodic migraine in a prioritized order and recommended doses for adult. Valproate should not be prescribed in women of childbearing age

From: Reference programme: diagnosis and treatment of headache disorders and facial pain. Danish Headache Society, 3rd edition, 2020

Drug Daily dose
Metoprolol/propranolol 50–200 mg/40–240 mg
Candesartancilexetil 16 (24–32) mg
Topiramate 25–100 (200) mg
Amitriptyline 10–100 mg
Flunarizin 5–10 mg
Valproate 500–1800 mg
Lisinopril 20 mg
Pitzotifen 1.5–3 mg
Riboflavin 400 mg
Magnesium 360 mg