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Table 6 Acute treatment of the migraine attack, first step: Simple analgesics and antiemetics with proven effects on the migraine attack and suggested initial doses [10]. These drugs can be used 2–3 times a day. Intake of combined analgesics should be limited to max. 9 days per month to avoid medication overuse headache. Tolfenamic acid 200 mg and diclofenac 50–100 mg can also be used

From: Reference programme: diagnosis and treatment of headache disorders and facial pain. Danish Headache Society, 3rd edition, 2020

Analgesics Initial Dose Antiemetics Initial Dose
Ibuprofen 400–600 mg Metoclopramide 10 mg
Naproxen 500 mg Domperidone 10 mg
Paracetamol 1.000 mg   
Aspirin/caffeine 500/50 mg