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Table 15 Pharmacological treatment of cluster headache

From: Reference programme: diagnosis and treatment of headache disorders and facial pain. Danish Headache Society, 3rd edition, 2020

Type Dose
Attack treatment:
 Inhalation of 100% oxygen 12–15 l/min via O2ptimask [36] w. 3 l reservoir or DVO mask
 Inj. sumatriptan 6 mg
 Sumatriptan nasal spray 20 mg
Preventive treatment
 Tablet verapamil retard Initially 100 mg × 2 for 3 days, hereafter 200 mg × 2. Possible further increase to 400–600 mg daily. Rarely up to 1000 mg
Transitional treatment
 Occipital nerve block (GON) / tablet prednisone Please refer to text
  1. DVO demand valve oxygen