Fig. 5

Summarized responses of both PPG and hemodynamic parameters to CCW electrical stimulation averaged over studied animals separately in each of three groups. Panels a – d show responses for the group that received infusion of saline, panels e – h for the group of valproate, and panels i – l for the group of sumatriptan. In all panels, yellow, red, and violet highlighting indicates pre-, during-, and post-stimulation phase, respectively. The time scale in seconds is shown in X-axis of each graphs, whereas the normalized parameters in a percentage are shown in Y-axes. The blue curve in each graph is the response of the measured parameter during the baseline stage, and the red curve is the response after an infusion of a respective substance. All curves were calculated as mean over three steps of the substance infusions