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Table 4 Differences in pressure pain thresholds for the preictal, ictal and postictal phase compared to the interictal phase in people with migraine (non-dominant site)

From: Fluctuations in local and widespread mechanical sensitivity throughout the migraine cycle: a prospective longitudinal study

   Crude Adjusteda
Mean 95% CI p-value Mean 95% CI p-value
Temporalis muscle Interictal 178.2 158.1–198.3 N/A 174.0 90.2–257.8 N/A
Preictal −29.4 −37.7 – − 21.0 <  0.001 −29.4 − 37.7 – − 21.0 <  0.001
Ictal − 52.5 − 60.8 – − 44.1 <  0.001 − 52.5 − 60.8 – − 44.1 <  0.001
Postictal −16.7 −25.1 – −8.4 <  0.001 − 16.7 − 25.1 – − 8.4 <  0.001
Paraspinal muscles C1 Interictal 225.5 193.9–257.2 N/A 180.3 49.1–257.8 N/A
Preictal −24.8 −35.7 – − 13.8 <  0.001 − 24.8 − 35.7 – − 13.8 <  0.001
Ictal −50.9 − 61.8 – − 30.9 <  0.001 − 50.9 − 61.8 – − 30.9 <  0.001
Postictal − 10.9 − 21.9 – − 0.004 0.050 −10.9 − 21.9 – - 0.004 0.050
Upper trapezius muscle Interictal 311.2 274.5–348.0 N/A 310.8 155.8–465.7 N/A
Preictal − 44.3 − 55.7 – − 32.9 <  0.001 − 44.3 −55.7 – − 32.9 <  0.001
Ictal −75.1 −86.5 – − 63.8 <  0.001 − 75.1 − 86.5 – − 63.8 <  0.001
Postictal −22.7 −34.1 – − 11.4 <  0.001 − 22.7 − 34.1 – − 11.4 <  0.001
Extensor carpi radialis muscle Interictal 238.9 211.0–266.9 N/A 242.5 126.6–358.3 N/A
Preictal −6.8 −19.4 – 5.7 0.279 −6.8 −19.4 – 5.7 0.279
Ictal −22.4 − 35.0 – − 9.9 0.001 − 22.4 − 35.0 – − 9.9 0.001
Postictal −12.7 −25.2 – − 0.2 0.047 − 12.7 − 25.2 – − 0.2 0.047
Tibialis anterior muscle Interictal 443.3 383.1–503.5 N/A 508.4 257.9–758.9 N/A
Preictal −31.7 −53.5 – − 9.9 0.005 − 31.7 − 53.5 – − 9.9 0.005
Ictal − 51.9 − 73.7 – − 30.0 < 0.001 − 51.9 − 73.7 – − 30.0 <  0.001
Postictal − 21.6 − 43.5 – 0.2 0.052 −21.6 −43.5 – 0.2 0.052
  1. CI confidence interval. Mean PPT (in kPa) compared to the interictal phase; negative values mean lower PPT scores compared to the interictal phase. aAdjusted for age
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