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Table 4 Differences in pressure pain thresholds for the preictal, ictal and postictal phase compared to the interictal phase in people with migraine (non-dominant site)

From: Fluctuations in local and widespread mechanical sensitivity throughout the migraine cycle: a prospective longitudinal study

  

Crude

Adjusteda

Mean

95% CI

p-value

Mean

95% CI

p-value

Temporalis muscle

Interictal

178.2

158.1–198.3

N/A

174.0

90.2–257.8

N/A

Preictal

−29.4

−37.7 – − 21.0

<  0.001

−29.4

− 37.7 – − 21.0

<  0.001

Ictal

− 52.5

− 60.8 – − 44.1

<  0.001

− 52.5

− 60.8 – − 44.1

<  0.001

Postictal

−16.7

−25.1 – −8.4

<  0.001

− 16.7

− 25.1 – − 8.4

<  0.001

Paraspinal muscles C1

Interictal

225.5

193.9–257.2

N/A

180.3

49.1–257.8

N/A

Preictal

−24.8

−35.7 – − 13.8

<  0.001

− 24.8

− 35.7 – − 13.8

<  0.001

Ictal

−50.9

− 61.8 – − 30.9

<  0.001

− 50.9

− 61.8 – − 30.9

<  0.001

Postictal

− 10.9

− 21.9 – − 0.004

0.050

−10.9

− 21.9 – - 0.004

0.050

Upper trapezius muscle

Interictal

311.2

274.5–348.0

N/A

310.8

155.8–465.7

N/A

Preictal

− 44.3

− 55.7 – − 32.9

<  0.001

− 44.3

−55.7 – − 32.9

<  0.001

Ictal

−75.1

−86.5 – − 63.8

<  0.001

− 75.1

− 86.5 – − 63.8

<  0.001

Postictal

−22.7

−34.1 – − 11.4

<  0.001

− 22.7

− 34.1 – − 11.4

<  0.001

Extensor carpi radialis muscle

Interictal

238.9

211.0–266.9

N/A

242.5

126.6–358.3

N/A

Preictal

−6.8

−19.4 – 5.7

0.279

−6.8

−19.4 – 5.7

0.279

Ictal

−22.4

− 35.0 – − 9.9

0.001

− 22.4

− 35.0 – − 9.9

0.001

Postictal

−12.7

−25.2 – − 0.2

0.047

− 12.7

− 25.2 – − 0.2

0.047

Tibialis anterior muscle

Interictal

443.3

383.1–503.5

N/A

508.4

257.9–758.9

N/A

Preictal

−31.7

−53.5 – − 9.9

0.005

− 31.7

− 53.5 – − 9.9

0.005

Ictal

− 51.9

− 73.7 – − 30.0

< 0.001

− 51.9

− 73.7 – − 30.0

<  0.001

Postictal

− 21.6

− 43.5 – 0.2

0.052

−21.6

−43.5 – 0.2

0.052

  1. CI confidence interval. Mean PPT (in kPa) compared to the interictal phase; negative values mean lower PPT scores compared to the interictal phase. aAdjusted for age