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Table 2 Differences in pressure pain thresholds for the preictal, ictal and postictal phase compared to the interictal phase in people with migraine (dominant side)

From: Fluctuations in local and widespread mechanical sensitivity throughout the migraine cycle: a prospective longitudinal study

  CrudeAdjusteda
Mean95% CIp-valueMean95% CIp-value
Temporalis muscleInterictal181.5159.0–201.0N/A163.970.4–257.5N/A
Preictal−30.7−39.9 - -21.5<  0.001− 30.7− 39.9 - -21.5<  0.001
Ictal−60.5−69.7- -51.3<  0.001−60.5−69.7- -51.3<  0.001
Postictal−16.1− 25.3- -6.90.001− 16.1− 25.3- -6.90.001
Paraspinal muscles C1Interictal225.7197.1–254.3N/A180.062.6–297.4N/A
Preictal−28.9− 40.2- -17.5<  0.001− 28.9−40.2- -17.5<  0.001
Ictal−61.4−72.8- -50.1< 0.001− 61.4− 72.8- -50.1<  0.001
Postictal−16.1− 27.5- -4.80.006−16.1−27.5- -4.80.006
Upper trapezius muscleInterictal312.2276.6–347.8N/A324.3175.0–473.6N/A
Preictal−48.0−60.5- -35.5<  0.001−48.0−60.5- -35.5<  0.001
Ictal−80.4−92.9- -67.9<  0.001−80.4−92.9- -67.9<  0.001
Postictal−24.0−36.5- -11.5<  0.001−24.036.5- -11.5<  0.001
Extensor carpi radialis muscleInterictal237.5211.6–263.3N/A249.1140.2–358.1N/A
Preictal−12.5−20.5- -4.40.003−12.5−20.5- -4.40.003
Ictal−20.4−28.5- -12.3<  0.001− 20.4− 28.5- -12.3<  0.001
Postictal−12.9−20.9- -4.80.002−12.9−20.9- -4.80.002
Tibialis anterior muscleInterictal441.4381.0–501.8N/A495.5243.0–747.9N/A
Preictal−30.1−50.5- -9.60.005− 30.1−50.5- -9.60.005
Ictal−47.9−68.3- -27.4<  0.001−47.9−68.3- -27.4<  0.001
Postictal−22.5−42.9- -2.00.032−22.5−42.9- -2.00.032
  1. CI confidence interval. Mean PPT (in kPa) compared to the interictal phase; negative values mean lower PPT scores compared to the interictal phase. aAdjusted for age
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