Table 2 Literatures on effects of low fat diet on migraine headache
From: Gut-brain Axis and migraine headache: a comprehensive review
Authors and year | Type of article | Sample size | Type of diet | Duration of treatment | Results |
|---|---|---|---|---|---|
Ferrara LA, Pacioni D, Di Fronzo V, Russo BF, Speranza E, Carlino V, et al. 2015 [53] | Crossover intervention trial | 83 episodic or chronic migraineurs (63 female and 20 male) | a low-lipid and a normal-lipid diet | 3 months + 3 months | Significant reduction in severity and number of migraine attacks |
Ramsden CE, Zamora D, Faurot KR, et al. 2013 | randomized trial | 67 patients with chronic daily headache (H3-L6 = 33, L6 = 34) | High omega-3 + low omega-6 fatty acid (H3-L6) or low omega-6 fatty acid (L6) | 12 weeks | Significant reduction in HIT score, headaches day per month, and headache hours per day in H3-L6 group |
Bic Z, Blix GG, Hopp HP, Leslie FM, Schell MJ. 1999 [135] | Clinical trial | 54 migraineurs | limit fat intake to no more than 20 g/day | 12 weeks | Significant decrease in headache frequency, intensity, and duration and medication intake |
Bunner AE, Agarwal U, Gonzales JF, Valente F, Barnard ND. 2014 | Crossover trial | 42 migraineurs | dietary instruction (a low-fat vegan diet) and placebo supplement | 36 weeks (16 weeks + 4 weeks washout+ 16 weeks) | Significant reduction in headache severity and frequency during the diet period |