Fig. 1From: Metabotropic glutamate receptor 5 regulates synaptic plasticity in a chronic migraine rat model through the PKC/NR2B signalRepeated IS infusions induced mechanical allodynia and thermal allodynia and upregulated the expression of CGRP in the rats. a The mechanical pain thresholds of the hind paw during the infusion of PBS/IS. b The thermal pain thresholds of the hind paw during the infusion of PBS/IS. c The protein expression of CGRP. (n = 6 in each group; *p < 0.05 compared with the sham group)Back to article page