Table 8 PRO Scores by TN Attack Frequency

Penn-FPS-R

n = 127

n = 58

n = 68

Mean (SD)

22.0 (29.5)

39.1 (32.1)

7.6 (16.9)

Median (IQR)

8.0 (0.0, 36.0)

34.0 (10.0, 64.0)

0.0 (0.0, 9.5)

Min/Max

0.0/120.0

0.0/120.0

0.0/89.0

PGIC, n (%)

n = 129

n = 59

n = 69

Very much improved

63 (49)

14 (24)

48 (70)

Much improved

39 (30)

26 (44)

13 (19)

Minimally improved

11 (9)

9 (15)

2 (3)

No change

6 (5)

2 (3)

4 (6)

Minimally worse

1 (1)

0

1 (1)

Much worse

5 (4)

4 (7)

1 (1)

Very much worse

4 (3)

4 (7)

0

BPI-SF (Intensity)

n = 129

n = 59

n = 69

Mean (SD)

1.39 (1.77)

2.62 (1.89)

0.36 (0.67)

Median (IQR)

0.50 (0.0, 2.25)

2.50 (1.0, 4.3)

0.00 (0.0, 0.50)

Min/Max

0.0/7.8

0.0/7.8

0.0/2.5

BPI-SF (Interference)

n = 129

n = 59

n = 69

Mean (SD)

1.05 (1.96)

2.10 (2.44)

0.18 (0.63)

Median (IQR)

0.00 (0.00, 1.14)

1.14 (0.00, 3.86)

0.00 (0.00, 0.00)

Min/Max

0.0/9.7

0.0/9.7

0.0/3.7

EQ-5D-5L -HUI UK weights

n = 129

n = 59

n = 69

Mean (SD)

0.864 (0.2)

0.790 (0.2)

0.927 (0.2)

Median (IQR)

0.939 (0.816, 1.000)

0.841 (0.741, 0.939)

1.000 (0.924, 1.000)

Min/Max

−0.075/1.000

0.049/1.000

−0.075/1.000

EQ-5D-5L-VAS

n = 129

n = 59

n = 69

Mean (SD)

72.6 (25.2)

66.4 (24.3)

77.5 (24.9)

Median (IQR)

81.0 (55.0, 94.0)

70.0 (50.0, 88.0)

90.0 (68.0, 95.0)

Min/Max

10/100

13/100

10/100

HADS Anxiety

n = 128

n = 58

n = 69

Mean (SD)

5.4 (4.3)

6.7 (4.6)

4.3 (3.8)

Median (IQR)

5.0 (2.0, 8.0)

6.0 (4.0, 10.0)

3.0 (1.0, 6.0)

Min/Max

0.0/21.0

0.0/21.0

0.0/15.0

HADS Depression

n = 128

n = 58

n = 69

Mean (SD)

3.7 (3.8)

5.1 (5.4)

2.6 (3.0)

Median (IQR)

2.0 (1.0, 5.0)

4.0 (0.0, 9.0)

1.0 (0.0, 4.0)

Min/Max

0.0/19.0

0.0/19.0

0.0/13.0