Fig. 8
From: Estrogen receptors α, β and GPER in the CNS and trigeminal system - molecular and functional aspects
GPER and CGRP distribution in the TG. Expression of GPER was observed in the cell membrane and cytoplasm in most neurons (arrow and arrowhead). Double immunohistochemistry with GPER and CGRP showed that most CGRP positive cells (arrowhead) also expressed GPER in the cytoplasm. Insert: higher magnification of a GPER positive cell, showing immunoreactivity in the cytoplasm and cell membrane