Table 1 Clinical and demographic features of study population at baseline

n

27

28

–

Age

39.2 ± 8.8

47.6 ± 10.9

0.002

Sex (female)

25 (92.6%)

24 (85.7%)

0.669

Duration of migraine (years)

22.6 ± 9.7

30.8 ± 12.1

0.013

Duration of chronic migraine (years)

–

12.2 ± 10.8

–

Duration of medication overuse (years)

–

8.6 ± 6.4

–

Migraine days per month

6.9 ± 2.4

23.6 ± 5.3

0.001

Headache days per month

7.2 ± 2.4

26.2 ± 5.2

0.001

Days of acute drug intake per month

6.7 ± 2.2

23.2 ± 5.6

0.001

Doses of acute drugs per month

7.2 ± 2.7

51.5 ± 60.5

0.001

Migraine with aura

5 (18.5%)

7 (25.0%)

0.746

Preventive therapy at baseline

10 (37.0%)

10 (35.7%)

1.000

Previous detoxification

–

32.1%

–

 NSAID

13 (48.1%)

14 (50.0%)

0.845

 Triptan

8 (29.6%)

7 (25.0%)

 Combination

4 (14.8%)

6 (21.4%)

 Politherapy

2 (7.4%)

1 (3.6%)