Prior preventive treatmentc | Antiepileptics N = 130 | Antihypertensives N = 62 | Tricyclic antidepressants N = 53 | OnabotulinumtoxinA N = 28 | SSRIs/SNRIs N = 27 |
---|---|---|---|---|---|
Reason for preventive treatment preference, n (%)d | Preferred fremanezumab n = 119 (91.5%) | Preferred fremanezumab n = 55 (88.7%) | Preferred fremanezumab n = 49 (92.5%) | Preferred fremanezumab n = 23 (82.1%) | Preferred fremanezumab n = 26 (96.3%) |
Reduces attack frequency | 100 (84.0) | 48 (87.3) | 40 (81.6) | 18 (78.3) | 20 (76.9) |
Reduces migraine intensity | 89 (74.8) | 38 (69.1) | 38 (77.6) | 17 (73.9) | 17 (65.4) |
Reduces attack duration | 81 (68.1) | 32 (58.2) | 32 (65.3) | 14 (60.9) | 15 (57.7) |
Reduces migraine-associated symptoms | 71 (59.7) | 27 (49.1) | 30 (61.2) | 14 (60.9) | 15 (57.7) |
Reduces migraine-associated disability | 74 (62.2) | 30 (54.5) | 27 (55.1) | 14 (60.9) | 16 (61.5) |
Causes less side effects | 78 (65.5) | 22 (40.0) | 33 (67.3) | 8 (34.8) | 12 (46.2) |
More convenient | 45 (37.8) | 23 (41.8) | 19 (38.8) | 8 (34.8) | 9 (34.6) |
Other | 1 (0.8) | 0 | 0 | 2 (8.7) | 2 (7.7) |