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Fig. 6 | The Journal of Headache and Pain

Fig. 6

From: Optogenetic stimulation of the motor cortex alleviates neuropathic pain in rats of infraorbital nerve injury with/without CGRP knock-down

Fig. 6

Burst firing rates in TN animals following optogenetic stimulation (a). Significant changes were observed in the TN-Opto-CGRP and TN-Opto-PBS groups. *, p < 0.05; **, analysis of variance (ANOVA). b, c Peri-event raster histogram of VPM neuron responses in the TN-Opto-CGRP and TN-Opto-PBS groups, respectively. VPM firing rates decreases during optical stimulation. Bin size = 50 ms. d, e Instantaneous firing frequency for VPM neurons in TN-Opto-CGRP and TN-Opto-PBS rats, respectively

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