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Table 4 Hazard rate ratios of dementia associated with migraine diagnoses grouped by sex or educational level (N = 62,578)

From: Mid- to late-life migraine diagnoses and risk of dementia: a national register-based follow-up study

Characteristics No. of individuals Dementia cases/person-years HR (95% CI) P value for interaction
Sex     0.6a
 Men
  Without migraine 13,617 186/102,687 1.00  
  With migraine 2882 57/21,913 1.39 (1.03–1.88)  
 Women
  Without migraine 38,104 454/299,319 1.00  
  With migraine 7975 150/62,013 1.54 (1.28–1.86)  
Educational level     0.8b
 Low
  Without migraine 17,757 292/147,296 1.00  
  With migraine 3799 92/31,028 1.47 (1.16–1.87)  
 Medium
  Without migraine 20,366 229/159,620 1.00  
  With migraine 4173 72/32,484 1.45 (1.11–1.89)  
 High
  Without migraine 13,598 119/95,090 1.00  
  With migraine 2885 43/20,414 1.64 (1.16–2.33)  
  1. In all models, any migraine diagnosis was investigated as exposure. All models were adjusted for sex, all other migraine diagnoses, country of origin, marital status, educational level, other headache diagnoses, psychiatric morbidities and Charlson Comorbidity Index
  2. HR Hazard rate ratios, 95% CI 95% confidence intervals
  3. a Interaction tested between migraine and sex
  4. b Interaction tested between migraine and educational levels