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Table 4 Median values of laboratory parameters in the whole sample and the comparison between patients with and without headache

From: Factors associated with the presence of headache in hospitalized COVID-19 patients and impact on prognosis: a retrospective cohort study

Variable

All patients

(n = 576)

Headache

(n = 137)

No headache

(n = 439)

p-value

Leukocytes at admission

6710 (4945–8885.00)

6290.00 (4682.50–8257.50)

6785.00 (5137.50–9302.50)

0.202

Worst leukocyte count

9425.00 (4442.50–14,182.50)

6245.00 (3875.00–11,422.50)

9975.00 (4722.50–14,625.00)

< 0.001

Lymphocytes at admission

990.00 (710.00–1387.50)

1117.00 (850.00–1495.00)

940.00 (680.00–1350.00)

0.003

Worst lymphocyte count

690.00 (430.00–1050.00)

910.00 (575.00–1220.00)

650.00 (410.00–990.00)

0.001

Platelets at admission

195,000.00 (156,000.00–257,000.00)

197,500.00 (170,500.00–240,750.00)

194,000.00 (149,000.00–264,000.00)

0.677

Worst platelet count

192,500.00 (137,000.00–341,250.00)

206,000.00 (163,000.00–384,500.00)

188,000.00 (134,000.00–333,500.00)

0.111

LDH at admission

285.00 (225.00–372.00)

263.00 (215.00–341.00)

292.50 (227.00–381.50)

0.019

Worst LDH value

285.00 (225.00–372.00)

301.50 (237.00–411.75)

365.00 (268.50–487.00)

< 0.001

CK at admission

83.00 (49.00–372.00)

72.00 (49.5–110)

86.00 (47.00–166.00)

0.605

Worst CK value

89.00 (53.25–179.75)

79.00 (49.00–136.00)

94.00 (55.50–192.00)

0.026

CRP at admission

65.90 (23.37–122.15)

40.55 (14.15–102.26)

73.40 (28.55–130.05)

0.002

Worst CRP value

105.00 (51.25–198.02)

67.90 (21.70–164.40)

113.40 (58.45–208.62)

< 0.001

PCT at admission

0.10 (0.06–0.26)

0.07 (0.04–0.14)

0.11 (0.07–0.30)

0.001

Worst PCT value

0.13 (0.06–0.43)

0.07 (0.04–0.18)

0.15 (0.08–0.54)

< 0.001

Worst ferritin value

979.00 (444.40–1819.00)

615.00 (306.80–1449.70)

1094.80 (534.75–1945.47)

< 0.001

Worst IL-6 value

27.80 (12.40–61.87)

17.95 (9.76–44.15)

33.50 (13.32–67.30)

0.001

D-Dimer at admission

761.50 (462.75–1369.00)

550.00 (380–864)

855.50 (515–50-1570.00)

0.001

Worst D-Dimer value

1300.00 (674.75–3231.75)

810.00 (504.50 (1458.50)

1534.00 (795.00–3580.00)

< 0.001

INR at admission

1.18 (1.10–1.29)

1.15 (1.08–1.23)

1.19 (1.11–1.32)

0.003

Worst INR value

1.25 (1.15–1.40)

1.19 (1.11–1.30)

1.26 (1.17–1.45)

< 0.001

  1. LDH Lactate dehydrogenase, CK Creatine Kinase, CRP C-reactive protein, PCT Procalcitonin, IL-6 interleukin 6, INR International normalized ratio. In bold, variables that were statistically significant after adjusting for multiple comparisons (threshold p < 0.0025)