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Table 3 Frequency of associated symptoms in the entire sample and the comparison between patients with and without headache

From: Factors associated with the presence of headache in hospitalized COVID-19 patients and impact on prognosis: a retrospective cohort study

Variable All patients (n = 576) Headache (n = 137) No Headache (n = 439) Adjusted p-value
Anosmia 146 (25.3%) 64 (46.7%) 82 (18.7%) < 0.001
Arthralgia 35 (6.1%) 18 (13.1%) 17 (3.9%) < 0.001
Asthenia 242 (42.1%) 70 (51.1%) 172 (39.2%) 0.014
Chest pain 99 (17.2%) 33 (24.1%) 66 (15.1%) 0.015
Cough 403 (70.2%) 113 (82.5%) 290 (66.2%) < 0.001
Cutaneous rash 11 (1.9%) 4 (2.9%) 7 (1.6%) 0.322
Diarrhea 192 (33.4%) 54 (39.4%) 138 (31.4%) 0.084
Dyspnea 292 (50.8%) 73 (53.3%) 219 (49.9%) 0.487
Expectoration 90 (15.7%) 24 (17.5%) 66 (15.0%) 0.484
Fever 462 (80.3%) 121 (88.3%) 341 (77.7%) 0.006
Lightheadedness 60 (10.4%) 19 (13.9%) 41 (9.3%) 0.001
Myalgia 139 (24.1%) 55 (40.1%) 85 (19.1%) < 0.001
Odynophagia 60 (10.4%) 22 (16.1%) 38 (9.7%) 0.892
Rhinorrhea 12 (2.1%) 2 (1.5%) 10 (2.3%) 0.558
Syncope 43 (7.5%) 9 (6.6%) 34 (7.7%) 0.648
Vomiting 47 (8.2%) 11 (8%) 136 (8.2%) 0.949
Weakness 90 (15.7%) 26 (19.0%) 64 (14.6%) 0.216
  1. In bold, variables that were statistically significant after adjusting for multiple comparisons (threshold p < 0.0029)
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