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Table 1 Frequency of baseline variables the entire sample and comparison between patients with and without headache

From: Factors associated with the presence of headache in hospitalized COVID-19 patients and impact on prognosis: a retrospective cohort study

Variable

All patients

(n = 576)

Headache

(n = 137)

No headache

(n = 439)

Adjusted p-value

Female sex

250 (43.3%)

80 (58.4%)

170 (38.7%)

< 0.001

Age (years)

67.2 (SD: 14.7)

59.25 (SD: 12.4)

69.6 (SD: 14.5)

< 0.001

Modified Rankin scale (mean)

0.61 (SD: 1.12)

0.15 (SD: 0.5)

0.75 (SD: 1.2)

< 0.001

Hypertension

300 (52.1%)

52 (38%)

248 (56.5%)

< 0.001

Diabetes

113 (19.6%)

20 (14.6%)

93 (21.2%)

0.090

Smoking

118 (20.5%)

20 (14.6%)

98 (22.3%)

0.050

Cardiological disorders

154 (26.7%)

19 (13.9%)

135 (30.8%)

< 0.001

Pulmonary disorders

145 (25.2%)

33 (24.1%)

112 (25.5%)

0.737

Cancer

94 (16.3%)

18 (13.1%)

76 (17.3%)

0.249

Immuno-suppression

24 (4.2%)

4 (2.9%)

20 (4.6%)

0.409

Chronic neurological disorders

105 (18.3%)

13 (9.5%)

92 (2%)

0.002

Prior history of headache

32 (5.6%)

15 (10.9%)

17 (3.9%)

0.002

ACEis /ARBs

215 (37.3%)

42 (30.7%)

173 (39.4%)

0.064

NSAIDs

75 (13%)

12 (8.8%)

66 (14.4%)

0.090

Corticosteroids

35 (6.1%)

7 (5.1%)

28 (6.4%)

0.587

Neuropharmacological treatment

203 (35.2%)

42 (30.7%)

161 (36.7%)

0.198

Time symptoms-ED (days)

7.34 (SD: 6.16)

8.51 (SD: 5.90)

6.98 (SD: 6.21)

0.011

  1. ACEis angiotensin-converting enzyme inhibitors, ARBs angiotensin II receptor blockers, NSAIDs non-steroidal anti-inflammatory drugs, ED Emergency department. In bold, variables that were statistically significant after adjusting for multiple comparisons (threshold p < 0.0029)