Altered hypothalamic functional connectivity in post-traumatic headache after mild traumatic brain injury

Table 2 Significant brain regions showing altered hypothalamus functional connectivity in mTBI patients compared with healthy controls

Brain region	BA	Peak MNI coordinates x,y,z (mm)	t value	Voxels
L hypothalamus
L fusiform gyrus	37	−36,-54,-18	−4.1003	17
L Rolandic operculum	45	−45,-12,18	−4.1043	48
R middle frontal gyrus	9	36,24,42	−3.8419	36
R medial superior frontal gyrus	10	12,33,42	−3.7560	27
R hypothalamus
R middle frontal gyrus	9	36,33,33	−4.6247	17
R postcentral gyrus	2	24,-39,72	−4.6080	23
L supplementary motor area	6	−9,-12,75	−4.4478	18

A corrected threshold of p<0.001 determined by Monte Carlo simulation was taken as measuring that there was significant difference between groups. BA Brodmann area; MNI Montreal Neurological Institute; L left; R right; mTBI mild traumatic brain injury

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