Skip to main content
Fig. 2 | The Journal of Headache and Pain

Fig. 2

From: Modulation of mechanosensory vibrissal responses in the trigeminocervical complex by stimulation of the greater occipital nerve in a rat model of trigeminal neuropathic pain

Fig. 2

Testing withdrawal responses to whisker pad mechanical stimulation with von Frey filaments shows a distinct time course over 3 weeks following unilateral (right side) CCI-IoN. The response score differed significantly between sham-operated (blue; n = 10) and CCI-IoN (magenta; n = 16) groups regarding Group (F1,107 = 28.906, p < 0.001) and Time (F3,6 = 4.217, p = 0.007), and also showed significant Group x Time interaction (F3,107 = 5.228, p = 0.002). Data represent means ± SEM, two-way ANOVA with repeated measures, Dunnett T3 post hoc test. Asterisks correspond to p < 0.05 (*), p < 0.01 (**), and p < 0.001 (***) for between-group comparisons. Within-group comparisons showed no changes in control cases, but a significant increase from baseline, pre-CCI values (#), over the three postsurgery testing days (p = 0.010, 0.003 and 0.001 for 7, 14, and 21 dps, respectively)

Back to article page