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Table 1 Migraine characteristics during the whole cycle and for each week of the cycle

From: Migraine start, course and features over the cycle of combined hormonal contraceptive users with menstrual migraine – temporal relation to bleeding and hormone withdrawal: a prospective diary-based study

PeriodMigraine daysDays with pain medicationMean Pain score/ migraine day
(range 1–3)
Number of attacks with a duration of 24 h
Complete cycle (28 Days)4.11 ± 2.813.25 ± 2.981.920.45 ± 0.72
Number week 1 (hormone-free interval)2.18 ± 1.591.61 ± 1.341.980.29 ± 0.53
Number week 2 (pill use)0.7 ± 0.980.55 ± 0.941.740.05 ± 0.21
Number week 3 (pill use)0.55 ± 0.960.50 ± 0.91.860.06 ± 0.21
Number week 4 (pill use)0.68 ± 1.190.61 ± 1.21.740.06 ± 0.24
P-value week 1 vs mean of week 2–4<  0.0001<  0.0001<  0.03<  0.0001
  1. Pain score 0–3: 0 = no pain; 3 = severe pain