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Table 1 Migraine characteristics during the whole cycle and for each week of the cycle

From: Migraine start, course and features over the cycle of combined hormonal contraceptive users with menstrual migraine – temporal relation to bleeding and hormone withdrawal: a prospective diary-based study

Period

Migraine days

Days with pain medication

Mean Pain score/ migraine day

(range 1–3)

Number of attacks with a duration of 24 h

Complete cycle (28 Days)

4.11 ± 2.81

3.25 ± 2.98

1.92

0.45 ± 0.72

Number week 1 (hormone-free interval)

2.18 ± 1.59

1.61 ± 1.34

1.98

0.29 ± 0.53

Number week 2 (pill use)

0.7 ± 0.98

0.55 ± 0.94

1.74

0.05 ± 0.21

Number week 3 (pill use)

0.55 ± 0.96

0.50 ± 0.9

1.86

0.06 ± 0.21

Number week 4 (pill use)

0.68 ± 1.19

0.61 ± 1.2

1.74

0.06 ± 0.24

P-value week 1 vs mean of week 2–4

<  0.0001

<  0.0001

<  0.03

<  0.0001

  1. Pain score 0–3: 0 = no pain; 3 = severe pain