From: Sentinel headache as a warning symptom of ischemic stroke
Associated risk factors | Patients with sentinel headache before stroke (n = 81) | Patients without sentinel headache before stroke (n = 469) | Р, OR, 95% CI |
---|---|---|---|
Mean age | 62,4 | 63,2 | 0.99 |
Females, n (%) | 52 (64.2%) | 200 (42.6%) | 0.001 2.4; (1.5–2.9) |
Smokers, n (%) | 25 (30.8%) | 211 (44.9%) | 0.02 0.6; (0.3–0.9) |
Аlcohol consumption, n (%) | 19 (23.4%) | 149 (31.7%) | 0.2 |
Low alcohol beverage, n (%) | 11 (13.6%) | 69 (14.7%) | 0.9 |
Strong alcohol beverage, n (%) | 12 (14.8%) | 107 (22.8%) | 0.1 |
Diabetes mellitus, n (%) | 11 (13.6%) | 73 (15.5%) | 0.7 |
Atrial fibrillation, n (%) | 19 (23.4%) | 66 (14.1%) | 0.04 1.9; (1.05–3.3) |
Body mass index > 25, n (%) | 57 (70.4%) | 316 (67.4%) | 0.7 |
Low physical activity, n (%) | 37 (45.7%) | 170 (36.2%) | 0.1 |
Angina pectoris, n (%) | 32 (39.5%) | 117 (24.9%) | 0.01 2.0; (1.2–3.2) |
Myocardial infarction, n (%) | 9 (11.1%) | 44 (9.4%) | 0.7 |
Arterial hypertension | 77 (95.0%) | 437 (93.2%) | 0.7 |
Stroke in first degree relatives, n (%) | 30 (37.0%) | 177 (37.7%) | 0.5 |
Peripheral artery disease, n (%) | 3 (3.7%) | 10 (2.1%) | 0.6 |
Large-artery atherosclerosis, n (%) | 18 (22.2%) | 136 (28.9%) | 0.2 |
Previous history of headache, n (%) | 71 (87.7%) | 299 (63.8%) | < 0.001 4.0; (2.0–8.0) |
Mean age of onset of previous headache | 37.8 | 42.9 | 0.8 |
Previous history migraine, n (%) | 22 (27.2%) | 62 (13.2%) | 0.002 2.5; (1.4–4.3) |
Previous history of TTH, n (%) | 63 (77.8%) | 281 (59.9%) | 0.003 2.3; (1.3–4.1) |