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Table 6 Probable risk factors in patients with sentinel headache compare to the patients without sentinel headache during one year before stroke

From: Sentinel headache as a warning symptom of ischemic stroke

Associated risk factorsPatients with sentinel headache before stroke (n = 81)Patients without sentinel headache before stroke (n = 469)Р, OR, 95% CI
Mean age62,463,20.99
Females, n (%)52 (64.2%)200 (42.6%)0.001
2.4; (1.5–2.9)
Smokers, n (%)25 (30.8%)211 (44.9%)0.02
0.6; (0.3–0.9)
Аlcohol consumption, n (%)19 (23.4%)149 (31.7%)0.2
Low alcohol beverage, n (%)11 (13.6%)69 (14.7%)0.9
Strong alcohol beverage, n (%)12 (14.8%)107 (22.8%)0.1
Diabetes mellitus, n (%)11 (13.6%)73 (15.5%)0.7
Atrial fibrillation, n (%)19 (23.4%)66 (14.1%)0.04
1.9; (1.05–3.3)
Body mass index > 25, n (%)57 (70.4%)316 (67.4%)0.7
Low physical activity, n (%)37 (45.7%)170 (36.2%)0.1
Angina pectoris, n (%)32 (39.5%)117 (24.9%)0.01
2.0; (1.2–3.2)
Myocardial infarction, n (%)9 (11.1%)44 (9.4%)0.7
Arterial hypertension77 (95.0%)437 (93.2%)0.7
Stroke in first degree relatives, n (%)30 (37.0%)177 (37.7%)0.5
Peripheral artery disease, n (%)3 (3.7%)10 (2.1%)0.6
Large-artery atherosclerosis, n (%)18 (22.2%)136 (28.9%)0.2
Previous history of headache, n (%)71 (87.7%)299 (63.8%)< 0.001
4.0; (2.0–8.0)
Mean age of onset of previous headache37.842.90.8
Previous history migraine, n (%)22 (27.2%)62 (13.2%)0.002
2.5; (1.4–4.3)
Previous history of TTH, n (%)63 (77.8%)281 (59.9%)0.003
2.3; (1.3–4.1)
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