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Table 6 Probable risk factors in patients with sentinel headache compare to the patients without sentinel headache during one year before stroke

From: Sentinel headache as a warning symptom of ischemic stroke

Associated risk factors

Patients with sentinel headache before stroke (n = 81)

Patients without sentinel headache before stroke (n = 469)

Р, OR, 95% CI

Mean age

62,4

63,2

0.99

Females, n (%)

52 (64.2%)

200 (42.6%)

0.001

2.4; (1.5–2.9)

Smokers, n (%)

25 (30.8%)

211 (44.9%)

0.02

0.6; (0.3–0.9)

Аlcohol consumption, n (%)

19 (23.4%)

149 (31.7%)

0.2

Low alcohol beverage, n (%)

11 (13.6%)

69 (14.7%)

0.9

Strong alcohol beverage, n (%)

12 (14.8%)

107 (22.8%)

0.1

Diabetes mellitus, n (%)

11 (13.6%)

73 (15.5%)

0.7

Atrial fibrillation, n (%)

19 (23.4%)

66 (14.1%)

0.04

1.9; (1.05–3.3)

Body mass index > 25, n (%)

57 (70.4%)

316 (67.4%)

0.7

Low physical activity, n (%)

37 (45.7%)

170 (36.2%)

0.1

Angina pectoris, n (%)

32 (39.5%)

117 (24.9%)

0.01

2.0; (1.2–3.2)

Myocardial infarction, n (%)

9 (11.1%)

44 (9.4%)

0.7

Arterial hypertension

77 (95.0%)

437 (93.2%)

0.7

Stroke in first degree relatives, n (%)

30 (37.0%)

177 (37.7%)

0.5

Peripheral artery disease, n (%)

3 (3.7%)

10 (2.1%)

0.6

Large-artery atherosclerosis, n (%)

18 (22.2%)

136 (28.9%)

0.2

Previous history of headache, n (%)

71 (87.7%)

299 (63.8%)

< 0.001

4.0; (2.0–8.0)

Mean age of onset of previous headache

37.8

42.9

0.8

Previous history migraine, n (%)

22 (27.2%)

62 (13.2%)

0.002

2.5; (1.4–4.3)

Previous history of TTH, n (%)

63 (77.8%)

281 (59.9%)

0.003

2.3; (1.3–4.1)