Fig. 1

Missing genetic component of migraine with aura. CADASIL: cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy, FASPS: familial advanced sleep-phase syndrome, FHM: familial hemiplegic migraine, GWAS: genome-wide association studies, NGS: next generation sequencing, RVCL-S: retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations