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Table 2 Association of cluster headache and coexisting migraine with anxiety

From: The impact of remission and coexisting migraine on anxiety and depression in cluster headache

 Any anxiety (GAD-7 scores ≥5)Moderate-to-severe anxiety (GAD-7 scores ≥10)
Crude OR (95% CI)PaOR (95% CI)PCrude OR (95% CI)PaOR (95% CI)P
Presence of CHa
 Controlreference reference reference reference 
 CH3.98 (2.41–6.57)< 0.0015.17 (2.93–9.12)< 0.0015.52 (2.72–11.20)< 0.0017.32 (3.35–15.99)< 0.001
Category of CH and migraineb
 Control without migrainereference reference reference reference 
 Control with migraine5.38 (2.18–13.25)< 0.0015.29 (2.10–13.29)< 0.0018.71 (1.73–43.71)0.0098.43 (1.65–42.96)0.01
 CH without migraine7.81 (3.95–15.43)< 0.0017.71 (3.84–15.49)< 0.00117.25 (4.09–72.73)< 0.00116.01 (3.77–68.03)< 0.001
 CH with migraine9.40 (3.50–25.22)0.0019.78 (3.55–26.92)0.00132.53 (6.73–157.12)< 0.00132.53 (6.63–159.64)< 0.001
  1. aAdjustment for age, female sex, current smoking, alcohol drinking, and coexisting migraine
  2. bAdjustment for age, female sex, current smoking, and alcohol drinking
  3. Abbreviations: aOR Multivariable-adjusted odds ratio; CH Cluster headache; CI Confidence interval; GAD-7 Generalized Anxiety Disorder (7-item scale); OR Odds ratio