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Table 2 Association of cluster headache and coexisting migraine with anxiety

From: The impact of remission and coexisting migraine on anxiety and depression in cluster headache

 

Any anxiety (GAD-7 scores ≥5)

Moderate-to-severe anxiety (GAD-7 scores ≥10)

Crude OR (95% CI)

P

aOR (95% CI)

P

Crude OR (95% CI)

P

aOR (95% CI)

P

Presence of CHa

 Control

reference

 

reference

 

reference

 

reference

 

 CH

3.98 (2.41–6.57)

< 0.001

5.17 (2.93–9.12)

< 0.001

5.52 (2.72–11.20)

< 0.001

7.32 (3.35–15.99)

< 0.001

Category of CH and migraineb

 Control without migraine

reference

 

reference

 

reference

 

reference

 

 Control with migraine

5.38 (2.18–13.25)

< 0.001

5.29 (2.10–13.29)

< 0.001

8.71 (1.73–43.71)

0.009

8.43 (1.65–42.96)

0.01

 CH without migraine

7.81 (3.95–15.43)

< 0.001

7.71 (3.84–15.49)

< 0.001

17.25 (4.09–72.73)

< 0.001

16.01 (3.77–68.03)

< 0.001

 CH with migraine

9.40 (3.50–25.22)

0.001

9.78 (3.55–26.92)

0.001

32.53 (6.73–157.12)

< 0.001

32.53 (6.63–159.64)

< 0.001

  1. aAdjustment for age, female sex, current smoking, alcohol drinking, and coexisting migraine
  2. bAdjustment for age, female sex, current smoking, and alcohol drinking
  3. Abbreviations: aOR Multivariable-adjusted odds ratio; CH Cluster headache; CI Confidence interval; GAD-7 Generalized Anxiety Disorder (7-item scale); OR Odds ratio