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Table 2 Migraine characteristics

From: A global real-world assessment of the impact on health-related quality of life and work productivity of migraine in patients with insufficient versus good response to triptan medication

Characteristic TIRs
(n = 483)
TRs
(n = 930)
All
(n = 1413)
p-valuea
Diagnosis, n (%)b,c     
 Migraine without aura 254 (52.6) 509 (54.7) 763 (54.0) 0.443
 Migraine with aura 201 (41.6) 363 (39.0) 564 (39.9) 0.347
 Menstrual/menstrual-related migraine 54 (11.2) 84 (9.0) 138 (9.8) 0.197
 Other 6 (1.2) 4 (0.4) 10 (0.7) 0.100
Migraine diagnosis based on ICHD criteria, n (%)     0.145
 Yes 253 (52.4) 436 (46.9) 689 (48.8)  
 No 125 (25.9) 271 (29.1) 396 (28.0)  
 Don’t know 105 (21.7) 223 (24.0) 328 (23.2)  
Migraine severityd over past 3 months, mean (SD)     
 Patient reported 6.6 (1.8) 5.5 (2.1) 5.9 (2.0) < 0.001
 Physician reported 6.2 (1.9) 5.2 (2.0) 5.6 (2.0) < 0.001
Headache days per month over past 3 months, mean (SD)     
 Patient reported 7.3 (±5.8) 4.3 (±3.8) 5.3 (±4.8) < 0.001
 Physician reported 7.0 (± 5.9) 4.4 (±4.1) 5.3 (±4.9) < 0.001
Chronic migraine (physician reported ≥15 headache days per month, over the past 3 months), n (%)c 56 (11.6) 30 (3.2) 86 (6.1) < 0.001
Timing of migraine, n (%)e     
 Morning (7 am–midday) 89 (18.8) 207 (22.6) 296 (21.3) 0.105
 Afternoon (midday–5 pm) 71 (15.0) 145 (15.8) 216 (15.5) 0.696
 Evening (5 pm–10 pm) 81 (17.1) 130 (14.2) 211 (15.2) 0.147
 During the night (10 pm-7 am) 40 (8.5) 46 (5.0) 86 (6.2) 0.012
 Occur at different times 266 (56.2) 489 (53.3) 755 (54.3) 0.302
 Do not know 15 (3.2) 20 (2.2) 35 (2.5) 0.264
Current symptoms, n (%)e     
 Pulsating/throbbing pain 369 (77.2) 683 (73.8) 1052 (75.0) 0.169
 Sensitivity to light 347 (72.6) 620 (67.0) 967 (68.9) 0.033
 Pain on one side of the head 318 (66.5) 648 (70.1) 966 (68.9) 0.176
 Nausea 349 (73.0) 606 (65.5) 955 (68.1) 0.004
 Sensitivity to sound 297 (62.1) 414 (44.8) 711 (50.7) < 0.001
 Pain worsened by activity/movement 242 (50.6) 350 (37.8) 592 (42.2) < 0.001
 Pain on both sides of the head 231 (48.3) 339 (36.6) 570 (40.6) < 0.001
 Vomiting 176 (36.8) 250 (27.0) 426 (30.4) < 0.001
 Sensitivity to smell 180 (37.7) 208 (22.5) 388 (27.7) < 0.001
 Visual aura/sight disturbance 166 (34.7) 191 (20.6) 357 (25.4) < 0.001
 Light-headedness/dizziness 144 (30.1) 151 (16.3) 295 (21.0) < 0.001
 Muscle weakness/fatigue 143 (29.9) 151 (16.3) 294 (21.0) < 0.001
 Pins needles/numbness 93 (19.5) 108 (11.7) 201 (14.3) < 0.001
 Kinesiophobia 76 (15.9) 73 (7.9) 149 (10.6) < 0.001
 Speech disturbance/ problems 49 (10.3) 36 (3.9) 85 (6.1) < 0.001
 Allodynia 37 (7.7) 41 (4.4) 78 (5.6) 0.010
  1. aP-values from test of two group difference: t-test for continuous variables and chi-square for categorical variables. bPhysicians could attribute more than one diagnosis to each patient if applicable. cPhysician reported. dReported severity using scale from 1 (very mild) to 10 (very severe). ePatient reported
  2. SD = standard deviation; TIR = triptan insufficient responder; TR = triptan responder