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Table 2 Migraine characteristics

From: A global real-world assessment of the impact on health-related quality of life and work productivity of migraine in patients with insufficient versus good response to triptan medication

Characteristic

TIRs

(n = 483)

TRs

(n = 930)

All

(n = 1413)

p-valuea

Diagnosis, n (%)b,c

    

 Migraine without aura

254 (52.6)

509 (54.7)

763 (54.0)

0.443

 Migraine with aura

201 (41.6)

363 (39.0)

564 (39.9)

0.347

 Menstrual/menstrual-related migraine

54 (11.2)

84 (9.0)

138 (9.8)

0.197

 Other

6 (1.2)

4 (0.4)

10 (0.7)

0.100

Migraine diagnosis based on ICHD criteria, n (%)

   

0.145

 Yes

253 (52.4)

436 (46.9)

689 (48.8)

 

 No

125 (25.9)

271 (29.1)

396 (28.0)

 

 Don’t know

105 (21.7)

223 (24.0)

328 (23.2)

 

Migraine severityd over past 3 months, mean (SD)

    

 Patient reported

6.6 (1.8)

5.5 (2.1)

5.9 (2.0)

< 0.001

 Physician reported

6.2 (1.9)

5.2 (2.0)

5.6 (2.0)

< 0.001

Headache days per month over past 3 months, mean (SD)

    

 Patient reported

7.3 (±5.8)

4.3 (±3.8)

5.3 (±4.8)

< 0.001

 Physician reported

7.0 (± 5.9)

4.4 (±4.1)

5.3 (±4.9)

< 0.001

Chronic migraine (physician reported ≥15 headache days per month, over the past 3 months), n (%)c

56 (11.6)

30 (3.2)

86 (6.1)

< 0.001

Timing of migraine, n (%)e

    

 Morning (7 am–midday)

89 (18.8)

207 (22.6)

296 (21.3)

0.105

 Afternoon (midday–5 pm)

71 (15.0)

145 (15.8)

216 (15.5)

0.696

 Evening (5 pm–10 pm)

81 (17.1)

130 (14.2)

211 (15.2)

0.147

 During the night (10 pm-7 am)

40 (8.5)

46 (5.0)

86 (6.2)

0.012

 Occur at different times

266 (56.2)

489 (53.3)

755 (54.3)

0.302

 Do not know

15 (3.2)

20 (2.2)

35 (2.5)

0.264

Current symptoms, n (%)e

    

 Pulsating/throbbing pain

369 (77.2)

683 (73.8)

1052 (75.0)

0.169

 Sensitivity to light

347 (72.6)

620 (67.0)

967 (68.9)

0.033

 Pain on one side of the head

318 (66.5)

648 (70.1)

966 (68.9)

0.176

 Nausea

349 (73.0)

606 (65.5)

955 (68.1)

0.004

 Sensitivity to sound

297 (62.1)

414 (44.8)

711 (50.7)

< 0.001

 Pain worsened by activity/movement

242 (50.6)

350 (37.8)

592 (42.2)

< 0.001

 Pain on both sides of the head

231 (48.3)

339 (36.6)

570 (40.6)

< 0.001

 Vomiting

176 (36.8)

250 (27.0)

426 (30.4)

< 0.001

 Sensitivity to smell

180 (37.7)

208 (22.5)

388 (27.7)

< 0.001

 Visual aura/sight disturbance

166 (34.7)

191 (20.6)

357 (25.4)

< 0.001

 Light-headedness/dizziness

144 (30.1)

151 (16.3)

295 (21.0)

< 0.001

 Muscle weakness/fatigue

143 (29.9)

151 (16.3)

294 (21.0)

< 0.001

 Pins needles/numbness

93 (19.5)

108 (11.7)

201 (14.3)

< 0.001

 Kinesiophobia

76 (15.9)

73 (7.9)

149 (10.6)

< 0.001

 Speech disturbance/ problems

49 (10.3)

36 (3.9)

85 (6.1)

< 0.001

 Allodynia

37 (7.7)

41 (4.4)

78 (5.6)

0.010

  1. aP-values from test of two group difference: t-test for continuous variables and chi-square for categorical variables. bPhysicians could attribute more than one diagnosis to each patient if applicable. cPhysician reported. dReported severity using scale from 1 (very mild) to 10 (very severe). ePatient reported
  2. SD = standard deviation; TIR = triptan insufficient responder; TR = triptan responder