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Table 1 Population characteristics by diagnosis

From: Cognitive aging in migraine sufferers is associated with more subjective complaints but similar age-related decline: a 5-year longitudinal study

 Without headache (WoH)Non migraine headache (NMH)Migraine headache (MH)Statisticsp-value
N2142435  
Follow-up timea
(yrs; median [P25th,P75th])
5.1 [4.7,5.3]5.0 [3.8,5.4]5.2 [4.9,5.3]W = 0.1920.909
Gender
(F:M; n(%))
126 (60%):9017 (70%):733 (94%):2χ2 = 17.430< 0.0001
Age at baseline
(yrs; mean ± sd)
65.8 ± 8.468.4 ± 6.861.1 ± 7.4F = 6.7410.001
Age at follow-up
(yrs; mean ± sd)
70.8 ± 8.573.0 ± 6.666.1 ± 7.3F = 6.2460.002
Literacy
(yrs; mean ± sd)
7.8 ± 4.26.5 ± 4.46.1 ± 4.2F = 3.0400.049
MMSEa
(median [P25th,P75th])
29 [28,30]28 [26,29]28 [27,29]W = 7.1430.028
GDSa
(median [P25th,P75th])
2 [1,5]3 [2,6]5 [3,8]W = 24.019< 0.0001
SMCQ
(mean ± sd)
6.2 ± 3.76.3 ± 4.18.3 ± 3.9F = 4.5840.010
Vascular Risk Factors
(0: 1: 2: ≥ 3; n)
25: 71: 144: 862: 10: 21: 144: 12: 27: 8χ2 = 4.2280.646
Cognitive decline
(Yes: No; n(%))
26 (12.0%):1903 (12.5%):212 (5.7%):33χ2 = 1.2430.537
Imaging data
 Brain MRI
(Yes: No; n(%))
122 (56.5%):9411 (45.8%):1328 (80.0%):7χ2 = 8.6150.013
 Fazekas score
(0-I: II-III; n(%))
82 (68.3%):386 (54.5%):516 (57.1%):12χ2 = 1.8730.392
 MTA
(0–1: 2–3; n(%))
111 (90.2%):1211 (100%):028 (100%):0χ2 = 4.1090.128
  1. Figures in bold represent statistically significant differences between one group and the others after Bonferroni post hoc test
  2. F females, M males, MMSE Mini Mental State Examination, MTA Medial Temporal Atrophy, GDS Geriatric Depression Scale, SMCQ Subjective Memory Complaints Questionnaire
  3. p ≤ 0.05 was considered significant
  4. askewness <− 1 or > 1
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