Table 1 Population characteristics by diagnosis

N

214

24

35

Follow-up time^a

(yrs; median [P25^th,P75^th])

5.1 [4.7,5.3]

5.0 [3.8,5.4]

5.2 [4.9,5.3]

W = 0.192

Gender

(F:M; n(%))

126 (60%):90

17 (70%):7

33 (94%):2

χ² = 17.430

Age at baseline

(yrs; mean ± sd)

65.8 ± 8.4

68.4 ± 6.8

61.1 ± 7.4

F = 6.741

Age at follow-up

(yrs; mean ± sd)

70.8 ± 8.5

73.0 ± 6.6

66.1 ± 7.3

F = 6.246

Literacy

(yrs; mean ± sd)

7.8 ± 4.2

6.5 ± 4.4

6.1 ± 4.2

F = 3.040

MMSE^a

(median [P25^th,P75^th])

29 [28,30]

28 [26,29]

28 [27,29]

W = 7.143

GDS^a

(median [P25^th,P75^th])

2 [1,5]

3 [2,6]

5 [3,8]

W = 24.019

SMCQ

(mean ± sd)

6.2 ± 3.7

6.3 ± 4.1

8.3 ± 3.9

F = 4.584

Vascular Risk Factors

(0: 1: 2: ≥ 3; n)

25: 71: 144: 86

2: 10: 21: 14

4: 12: 27: 8

χ² = 4.228

Cognitive decline

(Yes: No; n(%))

26 (12.0%):190

3 (12.5%):21

2 (5.7%):33

χ² = 1.243

 Brain MRI

(Yes: No; n(%))

122 (56.5%):94

11 (45.8%):13

28 (80.0%):7

χ² = 8.615

 Fazekas score

(0-I: II-III; n(%))

82 (68.3%):38

6 (54.5%):5

16 (57.1%):12

χ² = 1.873

 MTA

(0–1: 2–3; n(%))

111 (90.2%):12

11 (100%):0

28 (100%):0

χ² = 4.109