From: European Headache Federation recommendations for neurologists managing giant cell arteritis
Drug name | Mechanism of action |
---|---|
Abatacept | Humanized fusion protein that modifies co-stimulation in antigen presentation, inhibiting T-cell activity |
Anakinra | Monoclonal antibody to the IL-1β receptor |
Baricitinib | Synthetic DMARD, which targets the intracellular pro-inflammatory Janus kinase (JAK) family of enzymes |
Gevokizumab | Recombinant monoclonal antibody to IL-1β, a pro-inflammatory cytokine |
Rituximab | Chimeric monoclonal antibody against the protein CD20, which is primarily found on the surface of immune system B cells |