Migraine, headache, and mortality in women: a cohort study

Table 4 Age- and multivariable-adjusted hazard ratios for all-cause mortality according to migraine frequency (N = 27,844)

Migraine or headache status:	No migraine (N = 18,691)	Non-migraine headache (N = 4025)	Past history of migraine (N = 1518)	Active Migraine < 1/month (N = 2727)	Active migraine at least monthly (N = 703)	Active migraine weekly or daily (N = 180)
Migraine or headache status:	HR -ref-	HR (95% CI)	HR (95% CI)	HR (95% CI)	HR (95% CI)	HR (95% CI)
All-cause death,N	3614	641	306	356	73	22
Age-adjusted^a	1 (ref)	1.04 (0.96–1.13)	1.02 (0.91–1.15)	0.91 (0.82–1.02)	0.85 (0.68–1.08)	0.87 (0.58–1.33)
Multivariable-adjusted^b	1 (ref)	1.01 (0.93–1.10)	1.00 (0.89–1.12)	0.94 (0.84–1.05)	0.94 (0.74–1.19)	0.92 (0.61–1.40)

Abbreviations: HR Hazard ratio, CI Confidence interval, ref., reference category
^a_,Adjusted for age at baseline
^bAdjusted for the following variables measured at baseline: age, BMI, total cholesterol, smoking, alcohol use, physical activity, diabetes, hypertension, family history of myocardial infarction, and family history of cancer

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