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Table 2 Age- and multivariable-adjusted hazard ratios for all-cause and disease-specific mortality according to migraine or headache status (N = 27,844)

From: Migraine, headache, and mortality in women: a cohort study

Migraine or headache status:No history, (N = 18,691)Non-migraine headache, (N = 4025)Any migraine, (N = 5128)
HR -ref-HR (95% CI)HR (95% CI)
All-cause death,N3614641757
 Age-adjusteda1 (ref)1.04 (0.96–1.14)0.95 (0.87–1.02)
 Multivariable-adjustedb1 (ref)1.01 (0.93–1.10)0.96 (0.89–1.04)
Cardiovascular death,N2814659
 Age-adjusteda1 (ref)1.08 (0.79–1.48)1.05 (0.79–1.40)
 Multivariable-adjustedb1 (ref)0.99 (0.72–1.36)1.07 (0.81–1.42)
Cancer death,N861164199
 Age-adjusteda1 (ref)1.01 (0.86–1.20)0.96 (0.82–1.12)
 Multivariable-adjustedb1 (ref)1.02 (0.86–1.21)0.98 (0.84–1.15)
Female-specific cancer deathc, N2484153
 Age-adjusteda1 (ref)0.85 (0.61–1.19)0.86 (0.64–1.16)
 Multivariable-adjustedb1 (ref)0.87 (0.62–1.21)0.88 (0.65–1.19)
  1. Abbreviations: HR Hazard ratio, CI Confidence interval, ref, reference category
  2. a,Adjusted for age at baseline
  3. bAdjusted for the following variables measured at baseline: age, BMI, total cholesterol, smoking, alcohol use, physical activity, diabetes, hypertension, family history of myocardial infarction, and family history of cancer (categorizations described in detail in the Methods)
  4. cIncludes breast cancer, cervical cancer, endometrial cancer, ovarian cancer, and uterine cancer