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Table 3 Change from baseline in MIDAS absenteeism (days), presenteeism (days), and total lost productive days

From: Trajectory of migraine-related disability following long-term treatment with lasmiditan: results of the GLADIATOR study

 

Lasmiditan 100 mg (n = 972)

Lasmiditan 200 mg (n = 1063)

Change from BL*

Change from BL*

LS mean*

% change in mean

LS mean

% change in mean

Absenteeism (days)

BL, mean a

3.1

3.2

Month 3

−0.6

−20.2

−0.8

−25.1

Month 6

−0.9

−29.2

− 0.9

−29.5

Month 9

−1.0

−32.4

−1.0

−30.7

Month 12

−1.0

−32.4

−1.2

−38.6

Presenteeism (days)

BL, mean a

6.3

6.2

Month 3

−1.5

−24.1

−1.4

−21.7

Month 6

−2.1

−32.4

−1.8

−29.3

Month 9

−2.3

−36.1

−1.8

−29.6

Month 12

−2.6

−40.3

−2.3

−37.2

Total lost productive daysb

BL, mean

9.4

9.4

Month 3

−2.2

−23.4

−2.2

− 23.4

Month 6

−3.0

−31.9

−2.8

−29.8

Month 9

−3.3

−35.1

−2.8

−29.8

Month 12

−3.6

−38.3

− 3.5

−37.2

  1. Abbreviations: BL baseline; LS mean least squares mean
  2. *All changes from baseline significant at p < 0.001
  3. aCalculated as the sum of MIDAS question 1 (absenteeism from work or school) and question 2 (presenteeism at work or school). bIncludes patients with 0 total lost productive days at baseline