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# Table 6 Combination of genetic polymorphisms to predict risk of migraine. Calculation of joint PAR% using the SNPs showing noteworthiness during the computing of BFDP (BFDP < 0.8) or FPRP (FPRP< 0.2) at a statistical power to detect the OR of 1.5

From: Genetic variants in migraine: a field synopsis and systematic re-analysis of meta-analyses

Author, year | Gene/variant | Comparison | MAF | OR (95%CI) | P-value | Ethnicity | No. of cases/controls | PAR (%) | Joint PAR (%) |
---|---|---|---|---|---|---|---|---|---|

Chang X, 2018 [45] | NMUR2/rs72793414 | A vs. G | 0.1082 | 2.44 (1.85–3.23) | 3.81E-10 | Overall 2 | 1212/13494 | 13.4804396578 | 44.2094776354 |

Gormley P, 2016 [40] | LRP1/rs11172113 | C vs. T | 0.3894 | 0.90 (0.89–0.91) | 5.6E-49 | Caucasian 22 | 59,674/316078 | 4.0517761638 | |

Gormley P, 2016 [40] | PRDM 16/rs10218452 | G vs. A | 0.2264 | 1.11 (1.10–1.13) | 5.3E-38 | Caucasian 22 | 59,674/316078 | 2.4298861162 | |

Gormley P, 2016 [40] | FHL5/rs67338227 | T vs. A | 0.0220 | 1.09 (1.08–1.11) | 2.0E-27 | Caucasian 22 | 59,674/316078 | 0.1976087347 | |

Gormley P, 2016 [40] | TSPAN2/rs2078371 | C vs. T | 0.1252 | 1.11 (1.09–1.13) | 4.1E-24 | Caucasian 22 | 59,674/316078 | 1.3584908638 | |

Gormley P, 2016 [40] | PHACTR1/rs9349379 | G vs. A | 0.3774 | 0.93 (0.92–0.95) | 5.8E-22 | Caucasian 22 | 59,674/316078 | 2.7134848426 | |

Gormley P, 2016 [40] | MEF2D/rs1925950 | A vs. G | 0.4277 | 1.07 (1.06–1.09) | 9.1E-22 | Caucasian 22 | 59,674/316078 | 2.9068711836 | |

Gormley P, 2016 [40] | SLC24A3/rs4814864 | C vs. G | 0.3021 | 1.07 (1.06–1.09) | 2.2E-19 | Caucasian 22 | 59,674/316078 | 2.0709065394 | |

Gormley P, 2016 [40] | FGF6/rs1024905 | A vs. G | 0.3165 | 1.06 (1.04–1.08) | 2.1E-17 | Caucasian 22 | 59,674/316078 | 1.8636100452 | |

Gormley P, 2016 [40] | C7orf10/rs186166891 | T vs. A | 0.1631 | 1.09 (1.07–1.12) | 9.7E-16 | Caucasian 22 | 59,674/316078 | 1.4466644131 | |

Gormley P, 2016 [40] | PLCE1/rs10786156 | G vs. C | 0.4852 | 0.95 (0.94–0.96) | 2.0E-14 | Caucasian 22 | 59,674/316078 | 2.4863180765 | |

Gormley P, 2016 [40] | KCNK5/rs10456100 | T vs. C | 0.1813 | 1.06 (1.04–1.07) | 6.9E-13 | Caucasian 22 | 59,674/316078 | 1.0760942468 | |

Gormley P, 2016 [40] | HPSE2/rs12260159 | A vs. G | 0.1673 | 0.92 (0.89–0.94) | 3.2E-10 | Caucasian 22 | 59,674/316078 | 1.3565561475 | |

Gormley P, 2016 [40] | CFDP1/rs77505915 | A vs. T | 0.4898 | 1.05 (1.03–1.06) | 3.3E-10 | Caucasian 22 | 59,674/316078 | 2.3904576911 | |

Gormley P, 2016 [40] | RNF213/rs17857135 | C vs. T | 0.2115 | 1.06 (1.04–1.08) | 5.2E-10 | Caucasian 22 | 59,674/316078 | 1.2530981840 | |

Gormley P, 2016 [40] | NRP1/rs2506142 | G vs. A | 0.1865 | 1.06 (1.04–1.07) | 1.5E-09 | Caucasian 22 | 59,674/316078 | 1.1066169563 | |

Gormley P, 2016 [40] | GPR149/rs13078967 | C vs. A | 0.0110 | 0.87 (0.83–0.91) | 1.8E-09 | Caucasian 22 | 59,674/316078 | 0.1432047828 | |

Gormley P, 2016 [40] | SPINK2/rs7684253 | T vs. C | 0.4499 | 0.96 (0.94–0.97) | 2.5E-09 | Caucasian 22 | 59,674/316078 | 1.8325790934 | |

Gormley P, 2016 [40] | HEY2/rs1268083 | C vs. T | 0.4419 | 0.96 (0.95–0.97) | 5.3E-09 | Caucasian 22 | 59,674/316078 | 1.7994063059 | |

Gormley P, 2016 [40] | WSCD1/rs75213074 | T vs. C | 0.0094 | 0.89 (0.86–0.93) | 7.1E-09 | Caucasian 22 | 59,674/316078 | 0.1035070263 | |

Gormley P, 2016 [40] | GJA1/rs28455731 | T vs. G | 0.1302 | 1.06 (1.04–1.08) | 7.3E-09 | Caucasian 22 | 59,674/316078 | 0.7751445706 | |

Gormley P, 2016 [40] | ITPK1/rs11624776 | C vs. A | 0.2278 | 0.96 (0.94–0.97) | 7.9E-09 | Caucasian 22 | 59,674/316078 | 0.9195792057 | |

Gormley P, 2016 [40] | ADAMTSL4/rs6693567 | T vs. C | 0.3037 | 1.05 (1.03–1.06) | 1.2E-08 | Caucasian 22 | 59,674/316078 | 1.4957864823 | |

Gormley P, 2016 [40] | MED14/rs12845494 | G vs. C | 0.4114 | 0.96 (0.95–0.97) | 1.7E-08 | Caucasian 22 | 59,674/316078 | 1.6731330779 | |

Gormley P, 2016 [40] | LRRIQ3/rs1572668 | G vs. A | 0.4930 | 1.04 (1.02–1.05) | 2.1E-08 | Caucasian 22 | 59,674/316078 | 1.9338641980 | |

Gormley P, 2016 [40] | CARF/rs138556413 | G vs. A | 0.0104 | 0.88 (0.84–0.92) | 2.3E-08 | Caucasian 22 | 59,674/316078 | 0.1249559450 | |

Gormley P, 2016 [40] | ARMS2/rs2223089 | C vs. G | 0.1288 | 0.93 (0.91–0.95) | 3.0E-08 | Caucasian 22 | 59,674/316078 | 0.9098027819 | |

Gormley P, 2016 [40] | IGSF9B/rs561561 | T vs. A | 0.0827 | 0.94 (0.92–0.96) | 3.4E-08 | Caucasian 22 | 59,674/316078 | 0.4986744225 | |

Gormley P, 2016 [40] | NOTCH4/rs140002913 | A vs. G | 0.1150 | 0.91 (0.88–0.94) | 3.8E-08 | Caucasian 22 | 59,674/316078 | 1.0458242813 | |

Anttila V. 2013 [29] | PRDM16/rs2651899 | C vs. T | 0.4708 | 1.09 (1.07–1.12) | 3.28E-14 | Caucasian 19 | 23,285/95425 | 4.0649595346 | |

Anttila V. 2013 [29] | TSPAN2/rs12134493 | A vs. C | 0.0709 | 1.14 (1.10–1.18) | 6.71E-14 | Caucasian 19 | 23,285/95425 | 0.9828442876 | |

Anttila V. 2013 [29] | MEF2D/rs2274316 | C vs. A | 0.4289 | 1.07 (1.04–1.09) | 3.14E-08 | Caucasian 19 | 23,285/95425 | 2.9147892814 | |

Anttila V. 2013 [29] | TRPM8/rs7577262 | A vs. G | 0.2356 | 0.87 (0.84–0.90) | 3.27E-13 | Caucasian 19 | 23,285/95425 | 3.1595713513 | |

Anttila V. 2013 [29] | FHL5/rs13208321 | A vs. T | 0.2949 | 1.18 (1.13–1.24) | 2.15E-12 | Caucasian 19 | 23,285/95425 | 5.0406331131 | |

Anttila V. 2013 [29] | c7orf10/rs4379368 | T vs. C | 0.1961 | 1.11 (1.08–1.15) | 1.46E-09 | Caucasian 19 | 23,285/95425 | 2.1115517179 | |

Anttila V. 2013 [29] | MTDH/rs1835740 | C vs. T | 0.3510 | 1.18 (1.13–1.24) | 1.60E-11 | Caucasian 7 | 5950/50809 | 5.9425497094 |