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Table 5 Subgroup analysis results of genetic variants with statistically significance (P-value< 5*10−8) from GWAS studies based on migraine subtype

From: Genetic variants in migraine: a field synopsis and systematic re-analysis of meta-analyses

Author, yearGene/variantComparisonOR (95%CI)P-valueSubtypesNo. of cases/controlsFPRP Values at Prior probabilityBFDP 0.001BFDP 0.000001
OR 1.2OR 1.5
0.0010.0000010.0010.000001
Gormley P, 2016 [40]LRP1/rs11172113C vs. T0.85 (0.82–0.89)4.3E-16MO8348/1396225.365E-095.370E-064.295E-094.300E-064.578E-074.580E-04
Gormley P, 2016 [40]FHL5/rs7775721T vs. A1.15 (1.11–1.20)1.1E-12MO8348/1396221.253E-071.254E-041.222E-071.223E-041.210E-050.012
Gormley P, 2016 [40]ASTN2/rs6478241G vs. A1.14 (1.09–1.18)1.2E-10MO8348/1396229.555E-119.565E-089.538E-119.548E-081.305E-081.307E-05
Gormley P, 2016 [40]TRPM8/rs6724624G vs. C0.86 (0.82–0.90)1.1E-09MO8348/1396228.654E-088.662E-057.899E-087.906E-057.681E-067.630E-03
Gormley P, 2016 [40]PHACTR1/rs9349379G vs. A0.88 (0.85–0.92)2.1E-09MO8348/1396221.748E-050.0171.733E-050.0171.395E-030.583
Gormley P, 2016 [40]FGF6/rs1024905A vs. G1.12 (1.08–1.16)2.5E-09MO8348/1396222.451E-072.453E-042.451E-072.453E-042.680E-050.026
Gormley P, 2016 [40]TSPAN2/rs2078371C vs. T1.18 (1.12–1.25)7.4E-09MO8348/1396222.525E-050.0251.808E-050.0181.276E-030.561
Anttila V, 2013 [29]TRPM8/rs6741751A vs. G0.80 (0.75–0.86)8.64E-11MO7107/694271.094E-050.0111.469E-061.469E-031.143E-040.103
Anttila V, 2013 [29]LRP1/rs11172113C vs. T0.87 (0.84–0.91)9.96E-11MO7107/694271.300E-061.300E-031.260E-061.260E-031.117E-040.101
Anttila V, 2013 [29]PHACTR1/rs9349379G vs. A0.86 (0.82–0.90)2.81E-10MO7107/694278.654E-088.662E-057.899E-087.906E-057.681E-067.630E-03
Anttila V, 2013 [29]FHL5/rs11759769A vs. G1.18 (1.13–1.24)1.58E-12MO7107/694278.181E-088.189E-056.109E-086.115E-055.781E-065.753E-03
Anttila V, 2013 [29]MMP16/rs10504861T vs. C0.86 (0.81–0.90)1.17E-08MO7107/694278.654E-088.662E-057.899E-087.906E-057.681E-067.630E-03
  1. GWAS genome-wide association studies, MO migraine without aura
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