Table 1 Baseline demographics and clinical data of participants
From: TRPM8 genetic variant is associated with chronic migraine and allodynia
|  | Discovery cohort (n = 1077) | Replication cohort (n = 827) | p value | Combined (n = 1904) |
|---|---|---|---|---|
Age | 37.9 ± 12.6 | 37.0 ± 11.7 | 0.116 | 37.5 ± 12.2 |
Female sex | 827 (76.8) | 653 (79.0) | 0.259 | 1480 (77.7) |
Presence of aura | 180 (16.7) | 160 (19.3) | 0.137 | 340 (17.9) |
Chronic migraine | 332 (30.8) | 252 (30.5) | 0.868 | 584 (30.7) |
Disease duration of migraine (years) | 18.4 ± 11.2 | 18.1 ± 11.1 | 0.591 | 18.2 ± 11.1 |
HADS- anxiety score | 7.6 ± 4.0 | 7.4 ± 4.1 | 0.176 | 7.5 ± 4.0 |
HADS- depression score | 5.4 ± 3.7 | 5.1 ± 3.7 | 0.087 | 5.2 ± 3.7 |
PSQI- sleep score | 8.8 ± 4.0 | 9.0 ± 4.0 | 0.235 | 8.9 ± 4.0 |