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Table 1 Baseline demographics and clinical data of participants

From: TRPM8 genetic variant is associated with chronic migraine and allodynia

 Discovery cohort (n = 1077)Replication cohort (n = 827)p valueCombined
(n = 1904)
Age37.9 ± 12.637.0 ± 11.70.11637.5 ± 12.2
Female sex827 (76.8)653 (79.0)0.2591480 (77.7)
Presence of aura180 (16.7)160 (19.3)0.137340 (17.9)
Chronic migraine332 (30.8)252 (30.5)0.868584 (30.7)
Disease duration of migraine (years)18.4 ± 11.218.1 ± 11.10.59118.2 ± 11.1
HADS- anxiety score7.6 ± 4.07.4 ± 4.10.1767.5 ± 4.0
HADS- depression score5.4 ± 3.75.1 ± 3.70.0875.2 ± 3.7
PSQI- sleep score8.8 ± 4.09.0 ± 4.00.2358.9 ± 4.0
  1. Data were presented as n (%) or mean ± SD; N: number of participants; HADS: hospital anxiety and depression scale; PSQI: Pittsburgh sleep quality index
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