Table 2 Clinical features warning of a possible underlying disorder
From: Consensus of the Hellenic Headache Society on the diagnosis and treatment of migraine
| • Headache that peaks in severity in less than five minutes | |
| • New headache type versus a worsening of a previous headache | |
| • Change in previously stable headache pattern (e.g. progressive headache, worsening over weeks or longer) | |
| • Headache that changes with posture (e.g. standing up) | |
| • Headache awakening the patient | |
| • Headache precipitated by physical activity or Valsalva manoeuvre (e.g. coughing, laughing, straining) | |
| • First onset ≥50 years of age | |
| • Focal neurological symptoms or signs | |
| • Trauma | |
| • Fever | |
| • Seizures | |
| • History of malignancy | |
| • History of HIV or active infections |